A Clinicopathological Study of Abnormal Uterine Bleeding in Peri and Post Menopausal Age Group, with Special Emphasis on Early Diagnosis of Uterine Malignancy

Introduction: Abnormal uterine bleeding (AUB) continues to be one of the most frequently encountered problems in gynaecology. The present clinicopathological study was planned for early diagnosis and proper treatment of the organic pathology of the genital tract, with special emphasis on early diagnosis of malignancy. Material and Methods: The patients included in this study belong to Peri and Post menopausal age group starting from 40 years or, more and presenting with abnormal uterine bleeding. These patients were subjected to a detailed history and a meticulous general, systemic and local examination along with the relevant investigations including endometrial aspiration smear / microbiopsy, dilatation and curettage, and biopsy. Results: Total 300 patients were included in this study. Dysfunctional Uterine Bleeding and Menorrhagia were the most common diagnosis (39%) and complaint respectively. Out of 300 cases, 169 (56.3%) cases were managed surgically by total abdominal hysterectomy (138), vaginal hysterectomy (19) and extended hysterectomy (12). In the rest of 131 patients, 128 (42.6%) cases underwent diagnostic as well as therapeutic D and C and 3 cases were managed conservatively with radiotherapy. Fibroid uterus, chronic cervicitis and proliferative endometrium were the most common myometrial, cervical and endometrial histopathology respectively. Conclusion: All cases of AUB in the peri and post menopausal age group should be thoroughly analyzed including complete history, detailed clinical examination followed by appropriate radiological and pathological examination, especially in suspicious cases for early detection of premalignant and malignant lesions of the body of uterus, leading to early diagnosis and prompt treatment at appropriate time.